Circulating Lactonase Activity but Not Protein Level of PON-1 Predicts Adverse Outcomes in Subjects with Chronic Kidney Disease.

J Clin Med · 2019 · PMC6678354 · PMID 31311140

Europe PMC DOI

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0.1300

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did not reach statistical significancep = 0.13not close (p > 0.1)

Subjects in the lowest PON-1 protein adjusted lactonase activity quartile (<4.47 pmol/min/ng) showed similar trends (hazard ratio 1.71, 95% CI 1.03 to 2.85, p = 0.04; Table S3 ); however, after adjusting for traditional risk factors and medication this did not reach statistical significance (hazard ratio 1.51, 95% CI 0.89 to 2.55, p = 0.13; Table S3 ).

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