Wnt-11 as a Potential Prognostic Biomarker and Therapeutic Target in Colorectal Cancer.

Nevertheless, it is interesting to note that WNT11 mRNA expression also showed a trend for association with increased mortality ( Figure 1 d), which was significant only when combining expression with FZD6, RYK and/or PTK7 ( Figure 1 e).

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We found increased expression of FZD6, FZD7, RYK, and PTK7 in tumors, as well as a highly significant increase in FZD7 in tumor-adjacent cells ( Table 2 and Figure S1b ).

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