Delayed lupus nephritis in the course of systemic lupus erythematosus is associated with a poorer treatment response: a multicentre, retrospective cohort study in Japan.

On the basis that a poorer treatment response in D-LN patients could result in more frequent flares, we next evaluated renal relapse-free survival only in those who achieved CR within 6 months ( Figure 2(b) ). Although the difference did not reach statistical significance, LN relapses were relatively more frequent in D-LN compared with E-LN patients (log rank P = 0.171; HR 1.73, 95% CI 0.78–3.81, P = 0.176).

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