In contrast, expression of heme oxygenase-1 (HO-1), another target gene of Nrf2 ( 69 ), was found to correlate with thyroid cancer aggressiveness (stage and risk of recurrence, plus a near-significant trend for extra-thyroidal invasion), but not with tumor size or lymph node metastasis ( 70 ).
← all excerpts
Keap1/Nrf2 Signaling: A New Player in Thyroid Pathophysiology and Thyroid Cancer.
1
—
—