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Efficacy of low-dose D<sub>2</sub>/D<sub>3</sub> partial agonist pramipexole on neuroleptic-induced extrapyramidal symptoms and symptoms of schizophrenia: a stage-1 open-label pilot study.

Neuropsychiatr Dis Treat · 2019 · PMC6689661 · PMID 31496702

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an increasing trendno p-value reported
All the psychiatric rating scales showed an increasing trend on day 3 and at 1 week, which is due to the immediate deterioration of the symptoms in two subjects with akathisia.

also in 63,971 other papers

showed a trendno p-value reported
The psychiatric symptoms of schizophrenia showed a trend of improvement during the study, but there was no improvement in depressive mood.

also in 53,322 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.