The opioid epidemic: helping rheumatologists prevent a crisis.

RMD Open · 2019 · PMC6691510 · PMID 31452932

Europe PMC DOI

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a strong trendno p-value reported

4 Abuse and misuse Beyond the increase in deaths, studies note a strong trend towards the emergence of drug abuse with prescription opioids.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.