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Spinal Epidural Lipomatosis: A Review of Pathogenesis, Characteristics, Clinical Presentation, and Management.

Global Spine J · 2019 · PMC6693071 · PMID 31448201

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6 The number of steroid injections administered to a patient has shown a strong positive correlation with the incidence of SEL, 7 but a recent review attempting to determine the mean cumulative dose of prednisone prior to the onset of SEL failed to reach statistical significance. 8 Lynch et al reported a rare case of acute onset of bilateral lower limb weakness after glucocorticoid treatment for ulcerative colitis, implying that a patient’s sensitivity to steroid may also play a role in the development of SEL in addition to treatment duration, medication formulation, and

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.