Furthermore, analysis of genes downstream of ROS production, leading to control of the NLRP3 inflammasome complex and caspase 1 (in other hosts), also showed a trend of down-regulation (6 genes up-regulated and 14 genes down-regulated) with MEFV also identified as significant ( Table 1 ) ( Fig 4A and 4B ).
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Antibiotic treatment of Chlamydia-induced cystitis in the koala is linked to expression of key inflammatory genes in reactive oxygen pathways.
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