1,25-Dihydroxyvitamin D3 Prevents Epithelial-Mesenchymal Transition of HMrSV5 Human Peritoneal Mesothelial Cells by Inhibiting Histone Deacetylase 3 (HDAC3) and Increasing Vitamin D Receptor (VDR) Expression Through the Wnt/β-Catenin Signaling Pathway.

Also, cells exposed to high glucose plus LPS showed a trend for the morphological change to fibroblast-like cells, but 1,25(OH) 2 D3 converted the morphology of HMrSV5 to more typical mesothelial cells with a cobblestone-like growth pattern, which was similar to that in control group ( Figure 2C ).

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