CRISPR repeat sequences and relative spacing specify DNA integration by Pyrococcus furiosus Cas1 and Cas2.

Nucleic Acids Res · 2019 · PMC6698737 · PMID 31219587

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a significant trendno p-value reported

There was a significant trend wherein the highest plus strand peak was 30–31 bp from the highest minus strand peak for both plasmid DNA that contained (pCR7) or lacked (pControl) the CRISPR array (Figure 2B and C ).

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