Supplementation with Akkermansia muciniphila in overweight and obese human volunteers: a proof-of-concept exploratory study.

Nat Med · 2019 · PMC6699990 · PMID 31263284

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highly significantno p-value reported

The magnitude of the differences between either T0 versus T3 or versus the Placebo group (i.e., 866 cells/μl) is highly significant since a difference comprised between 300 to 1000 cells/μl is considered as clinically relevant 17 – 20 .

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did not reach statistical significanceno p-value reported

Waist circumference was decreased by about 1.56 cm, but this change did not reach statistical significance ( Fig. 4d ).

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