Targeted Derivation of Organotypic Glucose- and GLP-1-Responsive β Cells Prior to Transplantation into Diabetic Recipients.

Stem Cell Reports · 2019 · PMC6700523 · PMID 31378674

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psBCs transduced with both PDX1 and NEUROG3 showed a trend of enhanced C-peptide secretion upon high glucose stimulation, whereas transduction with NEUROG3 alone or MAFA + NEUROG3 led to no significant change in glucose-responsive C-peptide secretion.

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