Immunohistochemical Analysis of LGR5 and TROY Expression in Gastric Carcinogenesis Demonstrates an Inverse Trend

Iran Biomed J · 2019 · PMC6707110 · PMID 30501144

Europe PMC

hedged sentences

0.0001

closest p · 0.0× alpha

0.0950

boldest claim

The sentences

highly significantp < 0.0001actually significant

2A ), which resulted in a highly significant mean difference of the two molecules in the tumor tissue ( p < 0.0001, Fig. 2A ).

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borderline significantp = 0.052so close (0.05 < p ≤ 0.1)

On the other hand, TROY expression was higher in the tumor-adjacent normal tissue of the distal stomach (3.5 ± 1.1) versus the proximal (2.7 ± 0.8) region, which was borderline significant ( p = 0.052, Table 3 ).

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did not reach statistical significancep = 0.095so close (0.05 < p ≤ 0.1)

Accordingly, those with serum PGI/II ratio of ≤3.0 had higher levels of tumor LGR5 expression (3.9 ± 1.1), as compared to those above 3.0 (3.3 ± 1.0), which did not reach statistical significance ( p = 0.095, Table 3 ).

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