Anti-cyclic citrullinated peptide antibody is highly associated with rheumatoid factor and radiological defects in rheumatoid arthritis patients.

Finally, RA patients with low disease activity showed a trend, although insignificant, association with absence of extra-articular manifestations ( P = .066) (Table 3 ). 4 Discussion 4.1 Clinico-demographic and clinical characteristics In this study, we assessed the association between the status of anti-CCP antibody (positive or negative) with various clinico-demographic and laboratory characteristics in a cohort of 159 RA patients.

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