D-Dimer Predicts Disease Severity but Not Long-Term Prognosis in Acute Pulmonary Embolism.

Concerning these studies, their results do not warrant a significant trend, as some studies showed an association between D-dimer level and prognosis, 25 , 26 whereas others did not. 27 , 28 In general, a possible association between D-dimer and survival could be confounded by comorbidity, such as cancer. 29 Regarding our study, in which active cancer was rare, several other reasons might be responsible for the similar mortality rates in both D-dimer groups: first, the missing statistical significance could be due to the relatively small size of the cohort.

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