Impact of Resolution of Hyponatremia on Neurocognitive and Motor Performance in Geriatric Patients.

There were no between-group differences with respect to most components of the CGA upon admission, neither in the primary analysis group nor in the subgroups; a marginally significant difference (p = 0.045) was observed for the Timed Up and Go-Test (TuGT) in the hypovolemic group with a mean 33.00 s ± 18.44 s in the hyponatremia group vs. 19.64 s ± 7.81 s in the reference group (Supplemental Table 2 ).

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A clear trend to a more pronounced improvement in ADL was found in all 3 subgroups as compared to their references, but significance was reached only in the hypervolemic patients (14.29 ± 15.50 vs. 8.04 ± 12.42, p = 0.049).

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evaluated neurocognitive function by analyzing the response time to visual and auditory stimuli and found a highly significant reduction of the average latency by 8.6% when the patients were rendered normonatremic 14 .

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