Role of Aldosterone and Mineralocorticoid Receptor in Cardiovascular Aging.

Front Endocrinol (Lausanne) · 2019 · PMC6716354 · PMID 31507534

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Recently, a retrospective cohort study of the contemporary ORBIT-AF (Outcomes Registry for Better Informed Treatment of Atrial Fibrillation) registry showed that the use of MR antagonists was not associated with reduced atrial fibrillation, but showed a trend toward lower risk of stroke, transient ischemic attack, or systemic embolism ( 126 ).

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