Longitudinal diffusion tensor magnetic resonance imaging analysis at the cohort level reveals disturbed cortical and callosal microstructure with spared corticospinal tract in the TDP-43 G298S ALS mouse model.

Transl Neurodegener · 2019 · PMC6716821 · PMID 31485326

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showed a trendp = 0.1so close (0.05 < p ≤ 0.1)

Confirming the WBSS data, a significant FA reduction was observed at follow-up for the TDP-43 G298S mice in the right motor areas, whereas the left motor areas showed a trend ( p = 0.1) for FA reduction (Fig. 3 ).

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Longitudinal diffusion tensor magnetic resonance imaging analysis at the cohort level reveals disturbed cortical and callosal microstructure with spared corticospinal tract in the <i>TDP-43</i> <sup><i>G298S</i></sup> ALS mouse model.

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