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Evaluation of the safety and immunogenicity of the oral inactivated multivalent enterotoxigenic Escherichia coli vaccine ETVAX in Bangladeshi adults in a double-blind, randomized, placebo-controlled Phase I trial using electrochemiluminescence and ELISA assays for immunogenicity analyses.

Vaccine · 2019 · PMC6717083 · PMID 30473185

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a strong trendno p-value reported
A strong trend toward an adjuvant effect was also noted when the antigenic breadth of the plasma IgA response was evaluated, particularly when responses to 4 or more or 5 vaccine antigens were considered.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.