However, the highest plasma level of amoxicillin was significantly lower in the AMG group, which suggests an interaction between green tea polyphenols and the antibiotic. Comparing the AUC 0–240 for the two treatment groups (AM and AMG, N = 6 both) a slight decrease in amoxicillin absorption was observed in the AMG group, however, the difference did not reach statistical significance (Fig. 2 ).
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Effect of green tea on the gastrointestinal absorption of amoxicillin in rats.
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