Repurposed quinacrine synergizes with cisplatin, reducing the effective dose required for treatment of head and neck squamous cell carcinoma.

There was a difference in the time needed to reach maximum tumor volume between the combined quinacrine and 2 mg/kg cisplatin group and the 2 mg/kg cisplatin alone group of 4 days, however this did not reach statistical significance ( p = 0.6), possibly due to the small sample size and corrections for multiple comparisons.

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