Doxorubicin-loaded human serum albumin nanoparticles overcome transporter-mediated drug resistance in drug-adapted cancer cells.

However, the differences did not reach statistical significance.

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These experiments also confirmed that there is no significant difference in the anticancer activity between doxorubicin solution and doxorubicin nanoparticles in UKF-NB-3 cells, despite an apparent trend in the first set of experiments ( Figure 3 ).

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