Barely Significant
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Psoromic Acid, a Lichen-Derived Molecule, Inhibits the Replication of HSV-1 and HSV-2, and Inactivates HSV-1 DNA Polymerase: Shedding Light on Antiherpetic Properties.

Molecules · 2019 · PMC6720901 · PMID 31405197

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quite significantno p-value reported
Thus, it is quite significant that the results obtained by combining PA with ACV have led to potent anti-HSV-1 and anti-HSV-2 properties associated with potential reduced resistance.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.