Modulating Expression of Thioredoxin Interacting Protein (TXNIP) Prevents Secondary Damage and Preserves Visual Function in a Mouse Model of Ischemia/Reperfusion.

Of note, ASO-WT tended to show a higher level of TXNIP mRNA when compared to Scr-WT; however, it did not reach statistical significance.

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These findings are highly significant and clinically relevant, and could be translated to patients with ocular ischemia.

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