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A "human knockout" model to investigate the influence of the α-actinin-3 protein on exercise-induced mitochondrial adaptations.

Sci Rep · 2019 · PMC6722100 · PMID 31481717

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Consistent with their after-exercise RCAN1-4 results 14 , a 1.9-fold greater calcineurin activity in exercised KO compared with WT muscles was also observed, although this difference did not reach statistical significance.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.