Eradication of <i>Pseudomonas aeruginosa</i> with inhaled colistin in adults with non-cystic fibrosis bronchiectasis.

11 , 14 , 22 Besides, in one of the most important clinical trials of aerosolized antibiotics for patients with NCFB, a clear trend of increase of time to first exacerbation was demonstrated when patients with good adherence to treatment were selected. 12 Our results are consistent with a recent study that showed that an important risk factor predicting benefit from inhaled antibiotics is a history of frequent pulmonary exacerbations. 30 In our case, 70% of the patients had >2 exacerbations in the previous year, while 40% of the patients in the clinical trial had no exacerbations in the previous year.

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