Barely Significant
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The Effect of Aclidinium on Symptoms Including Cough in Chronic Obstructive Pulmonary Disease: A Phase 4, Double-Blind, Placebo-controlled, Parallel-Group Study.

Am J Respir Crit Care Med · 2019 · PMC6727161 · PMID 30951372

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Improvements in respiratory-specific quality-of-life measures (LCQ and CAT) did not reach statistical significance for aclidinium versus placebo in the total patient population.

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a numerical trendno p-value reported
In contrast to the total population, when patients were stratified by cough severity, there was a numerical trend toward improvement in LCQ in patients with more severe cough versus less severe cough.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.