Plasma total fibroblast growth factor 23 levels are associated with acute kidney injury and mortality in children with acute respiratory distress syndrome.

In this analysis, although the p-value for the indirect effect did not reach statistical significance (p = 0.12), likely contributed to by decreased sample size, it was estimated that 36.4% of the association between total FGF23 and AKI was explained by IL-6 ( S2 Table ), suggesting partial mediation.

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