The insulin treatment increased phosphorylation of IRS-1 Ser307 in both db/m and db/db mice; however, this difference did not reach statistical significance ( Figs. 6 C, 6 D).
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The Diurnal Rhythm of Insulin Receptor Substrate-1 (IRS-1) and Kir4.1 in Diabetes: Implications for a Clock Gene Bmal1.
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