Elderly Bleeding Risk of Direct Oral Anticoagulants in Nonvalvular Atrial Fibrillation: A Systematic Review and Meta-Analysis of Cohort Studies.

Drugs R D · 2019 · PMC6738514 · PMID 31127504

Europe PMC DOI

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did not reach statistical significanceno p-value reported

Further, when bleeding risk was assessed between apixaban and dabigatran, dabigatran had a 41% greater risk than apixaban for a major bleed (HR 1.41 [95% CI 0.93–2.14]) but did not reach statistical significance [ 20 ].

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