Increased expression of heme-binding protein 1 early in Alzheimer's disease is linked to neurotoxicity.

Elife · 2019 · PMC6739868 · PMID 31453805

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did not reach statistical significanceno p-value reported

However, this increase did not reach statistical significance.

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highly significantno p-value reported

This finding is highly significant given that vascular damage progressively worsens over the course of AD progression which, in turn, contribute to rising heme levels that will ultimately contribute to progressive neuronal loss (Ghiso et al., 2010).

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