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Models of Variability and Circadian Rhythm in Heart Rate, Blood Pressure, and QT Interval for Healthy Subjects Who Received Placebo in Phase I Trials.

Clin Transl Sci · 2019 · PMC6742942 · PMID 31021448

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showed a trendno p-value reported
Visual inspection showed a trend for decline in the peaks and troughs of the QT circadian rhythms within the assessed timeframe.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.