Within-host evolution of bovine Staphylococcus aureus selects for a SigB-deficient pathotype characterized by reduced virulence but enhanced proteolytic activity and biofilm formation.

Sci Rep · 2019 · PMC6748969 · PMID 31530887

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a clear trendno p-value reported

However, we found a clear trend towards reduced virulence of the HA isolate, as one would expect in chronic, persistent infections 48 .

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