A placebo-controlled study comparing the efficacy of intra-articular injections of hyaluronic acid and a novel hyaluronic acid-platelet-rich plasma conjugate in a canine model of osteoarthritis.

J Orthop Surg Res · 2019 · PMC6749694 · PMID 31533754

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a clear trendno p-value reported

Our findings confirm the beneficial clinical effects of HMW-HA by both subjective and objective parameters at 10, 12, and 20 weeks compared to the saline control group including gross and histological grades of the synovium and a clear trend showing less severe articular cartilage lesions assessed grossly and histologically when compared with the control group.

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