Excessive Accumulation of Ca<sup>2 +</sup> in Mitochondria of Y522S-RYR1 Knock-in Mice: A Link Between Leak From the Sarcoplasmic Reticulum and Altered Redox State.

Front Physiol · 2019 · PMC6755340 · PMID 31607937

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Semiquantitative WB analysis showed a trend to increase in TOM20/actin ratio ( P = 0.05), which suggests an increase in mitochondrial number or mitochondrial dimensions in YS compared to WT fibers of FDB muscles ( Figure 4A ).

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