Efficacy of inhaled ciprofloxacin agents for the treatment of bronchiectasis: a systematic review and meta-analysis of randomized controlled trials.

14 RESPIRE 2 showed only trends in improving the two primary outcomes, but both regimens did not reach statistical significance. 15 Statistical analysis for the two RESPIRE studies were almost the same, except that α corrections were differently applied (a significance level of 0.025 for each treatment arm in RESPIRE 1, and 0.049 for the 14-day on/off arm and 0.001 for the 28-day on/off arm in RESPIRE 2). 15 Among trials ev

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