Radiofrequency, chemotherapy, resection and orthotropic liver transplantation are curative treatments advisable in the early stages of the disease [ 1 ], while patients in advanced stage(s) are recommended to be treated with Sorafenib, which exhibits a moderately significant increase in patient survival [ 2 ].
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Forcing ATGL expression in hepatocarcinoma cells imposes glycolytic rewiring through PPAR-α/p300-mediated acetylation of p53.
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