In this study, we found that the levels of RhoA-GTP were significantly higher in pR5 compared to Wt mice (p=0.0021) and attenuated in pR75KO mice (p=0.0411) compared to pR5 mice while p75KO had slightly higher level than pR5 on the blot but did not reach statistical significance ( Figure 3D ).
← all excerpts
Knockout of p75 neurotrophin receptor attenuates the hyperphosphorylation of Tau in pR5 mouse model.
1
—
—