For the CR + inter-neuron density [Figure 3 D], while a significant main effect of sub-region was observed ( F (2, 42) = 52.43, P < 0.001), neither the main effect of group ( F (1, 42) = 0.040, P = 0.843) nor the group × sub-region interaction ( F (2, 42) = 0.115, P = 0.892) approached significance in aged mice.
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Adolescent stress increases depression-like behaviors and alters the excitatory-inhibitory balance in aged mice.
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