Peripheral Innate Immune Activation Correlates With Disease Severity in <i>GRN</i> Haploinsufficiency.

Front Neurol · 2019 · PMC6759464 · PMID 31620075

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nearly significantp = 0.05actually significant

There was a nearly significant association between elevated plasma sCD14 and decreased white matter integrity in the left middle temporal gyrus ( p = 0.05, FWE corrected), and elevated plasma IL-18 was associated with decreased gray matter in the middle occipital gyrus ( p = 0.033, FWE corrected).

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