Prior Activation of 5-HT7 Receptors Modulates the Conditioned Place Preference With Methylphenidate.

Front Behav Neurosci · 2019 · PMC6759476 · PMID 31619973

Europe PMC DOI

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0.0653

closest p · 1.3× alpha

0.0653

boldest claim

The sentences

a significant trendP = 0.0653so close (0.05 < p ≤ 0.1)

Results Experiment 1: The Multidose Pilot Locomotor Activity Dose-related pharmacological effect on locomotor activity, after treatment with TP-22, showed a significant trend ( F (3,38) = 2.612, P = 0.0653), confirmed by post hocs (see below), whereas interaction between time and treatment did not show significance ( F (21,266) = 0.769, P = 0.7570).

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marginally significantno p-value reported

In the first experiment, we characterized a range of TP-22 dosages by means of a recording rack, and found that the 0.25 mg/kg dose was the most effective in altering locomotor activity: the observed increase, although marginally significant in the ANOVA, was however fully significant by Tukey post hoc analysis.

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