Analysis of five prostate cancer genome datasets using the cBioportal data source ( http://www.cbioportal.org/ ) suggest that ARID4B and PTEN deletions tend to be mutually exclusive in the prostate cancer genome, although the relationship did not reach statistical significance ( P > 0.05) (Supplementary Table 3 ).
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Identification of the PTEN-ARID4B-PI3K pathway reveals the dependency on ARID4B by PTEN-deficient prostate cancer.
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