Ozone effects on blood biomarkers of systemic inflammation, oxidative stress, endothelial function, and thrombosis: The Multicenter Ozone Study in oldEr Subjects (MOSES).

PLoS One · 2019 · PMC6760801 · PMID 31553765

Europe PMC DOI

hedged sentences

0.0130

closest p · 0.3× alpha

0.0480

boldest claim

The sentences

marginally significantp = 0.013actually significant

We found a marginally significant interaction between ozone and age for monocyte-platelet conjugates (p = 0.013, Tables Oo and Pp in S1 Appendix ).

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marginally statistically significantp = 0.017actually significant

In linear regression analysis, ozone effects on nitrotyrosine were marginally statistically significant (p = 0.017).

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marginal significancep = 0.017actually significant

Nitrotyrosine, a marker of oxidative and nitrosative stress, decreased with increasing ozone concentrations, with marginal significance (120 vs 0 ppb: -41.5, CI -70.1, -12.8; 70 vs 0 ppb: -14.2, CI -42.7, 14.2; p = 0.017).

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did not reach statistical significancep = 0.048actually significant

Fibrinogen decreased with 70 ppb ozone (-157 ug/mL) and increased with 120 ppb ozone (317 ug/mL) relative to 0 ppb ozone exposure, but this did not reach statistical significance (p = 0.048).

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