Histamine2-Receptor Antagonists, Proton Pump Inhibitors, or Potassium-Competitive Acid Blockers Preventing Delayed Bleeding After Endoscopic Submucosal Dissection: A Meta-Analysis.

Front Pharmacol · 2019 · PMC6761621 · PMID 31607912

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slightly significantno p-value reported

Direct comparisons showed slightly significant efficacy in PPIs rather than H 2 RAs in preventing post-ESD bleeding [OR: 1.83; 95% confidence interval (CI): 1.10 to 3.05] and vonoprazan was better than PPIs (OR: 0.46; 95% CI: 0.25 to 0.86).

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