Chromosome-wide co-fluctuation of stochastic gene expression in mammalian cells.

Furthermore, after grouping ATAC peak pairs into 100 equal-interval bins according to the genomic distance between peaks, we observed a clear trend that δ a decreases with the genomic distance between peaks ( ρ = -0.05 for unbinned data, P < 0.001, within-chromosome shuffling test; Fig 3E ).

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Although many statistical results in this study are highly significant, the effect sizes appear small in several analyses, most notably the δ e and δ a values for linked genes.

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