Inhibition of Kirsten-Ras reduces fibrosis and protects against renal dysfunction in a mouse model of chronic folic acid nephropathy.

Sci Rep · 2019 · PMC6768870 · PMID 31570767

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did not achieve significanceno p-value reported

The active K-Ras ASO also reduced fibrosis as compared to the control oligo but this difference did not achieve significance (Supplementary Fig.

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showed a trendno p-value reported

The K-Ras ASO phenotypic impact showed a trend to improvement when compared to the unrelated control oligo but this did not achieve significance due to the scatter of the in vivo data.

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