Why Secondary Analyses in Vitamin D Clinical Trials Are Important and How to Improve Vitamin D Clinical Trial Outcome Analyses-A Comment on "Extra-Skeletal Effects of Vitamin D, <i>Nutrients</i> 2019, <i>11</i>, 1460".

The fact that both RCTs enrolled large numbers of participants meant that they could obtain results for various subgroups, and, indeed, both papers reported that subgroups had significant or nearly significant reductions in disease outcomes from vitamin D supplementation, as shown in Table 1 .

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