The combination of NPM1, DNMT3A, and IDH1/2 mutations leads to inferior overall survival in AML.

Am J Hematol · 2019 · PMC6771683 · PMID 31145495

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showed a trendno p-value reported

Triple mutation of NPM1, DNMT3A and IDH1/2 showed a trend towards inferior overall survival in our discovery dataset, and was significantly associated with reduced OS in a large independent validation cohort.

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