26 When this study was removed in a sensitivity analysis, heterogeneity decreased and the observed risk increase became nominally significant (1.30, 1.06 to 1.58).
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Benefits and harms of lower blood pressure treatment targets: systematic review and meta-analysis of randomised placebo-controlled trials.
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Differences between primary prevention and CAD trials were significant or borderline significant for all efficacy outcomes except stroke ( online supplementary eFigures 2–7 ).