Although this tendency did not reach statistical significance, it is in line with a previous study that also found propionate (0.5 mM) to inhibit GSIS in perifused rat islets. 36 However, that study also found propionate to inhibit insulin secretion at low glucose levels, which we were not able to detect in our setup.
← all excerpts
Short-chain fatty acids and regulation of pancreatic endocrine secretion in mice.
1
—
—